Phone: (626) 815-6000, Ext. 3353
Email: shuang@apu.edu
Office Location: Wynn, Room 209
Office Hours: Monday and Wednesday, 11 a.m. to 12 p.m.
Kevin Huang, Ph.D.
Assistant Professor, Department of Biology and Chemistry
College of Liberal Arts and Sciences
Profile
Kevin Sheng-Lin Huang, Ph.D., is an assistant professor in the Department of Biology and Chemistry. His areas of expertise include solid phase organic synthesis, mechanistic physical organic chemistry, and research for undergraduates and high school students in chemical sciences. Huang is involved in the Project SEED Program, "Role of Organic Synthesis in Drug Discovery," sponsored by The American Chemical Society (ACS) and Azusa Pacific University, which offers opportunities to outreach to the Azusa community and to promote diversity in the field of science.
Education
Ph.D. - University of California, Davis, 2002
B.S. - University of California, Irvine, 1996
B.S. - University of California, Irvine, 1996
Professional/Scholarly Presentations
Presentations
Huang, K., Schmeing, T., Kitchen, D., Steitz, T., Moore, P., and Strobel, S. "Investigating the ribosome catalyzed peptide bond formation using transition state mimics," 2004 RNA Society Meeting, University of Wisconsin, 2004
Huang, K., Butler, E., Schmeing, T., Kitchen, D., Steitz T., and Strobel, S. "Defining the regio- and stereospecificity of the peptidyl transferase reaction," 2005 RNA Society Meeting, Banff, Canada, 2005
Publications
Schmeing, T., Huang,K., Strobel, S., and Steitz, T. "The mechanism of peptidyl transferase as defined by the structure of improved ground and transition state complexes with the 50S subunit," Molecular Cell, 20, (2005): 437-448.
Schmeing, T., Huang, K., Strobel, S., and Steitz, T. "An induced fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA," Nature, 438, (2005): 520-524.
Huang, K., Weinger, J., Butler, E., and Strobel, S. "Regiospecificity of the peptidyl tRNA ester within the ribosomal P-site," Journal of the American Chemical Society, 128, (2006): 3108-3109.
Huang, K., Haddadin, M., and Kurth, M. "Imidazo- and Pyridolpyrimidium bromides: synthesis and hydrolysis," Journal of Organic Chemistry, 67, (2002): 2382-2385.
Huang, K., Schmeing, T., Kitchen, D., Steitz, T., Moore, P., and Strobel, S. "Investigating the ribosome catalyzed peptide bond formation using transition state mimics," 2004 RNA Society Meeting, University of Wisconsin, 2004
Huang, K., Butler, E., Schmeing, T., Kitchen, D., Steitz T., and Strobel, S. "Defining the regio- and stereospecificity of the peptidyl transferase reaction," 2005 RNA Society Meeting, Banff, Canada, 2005
Publications
Schmeing, T., Huang,K., Strobel, S., and Steitz, T. "The mechanism of peptidyl transferase as defined by the structure of improved ground and transition state complexes with the 50S subunit," Molecular Cell, 20, (2005): 437-448.
Schmeing, T., Huang, K., Strobel, S., and Steitz, T. "An induced fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA," Nature, 438, (2005): 520-524.
Huang, K., Weinger, J., Butler, E., and Strobel, S. "Regiospecificity of the peptidyl tRNA ester within the ribosomal P-site," Journal of the American Chemical Society, 128, (2006): 3108-3109.
Huang, K., Haddadin, M., and Kurth, M. "Imidazo- and Pyridolpyrimidium bromides: synthesis and hydrolysis," Journal of Organic Chemistry, 67, (2002): 2382-2385.
Professional Experience
Academic Experience
National Institute of Health Postdoctoral Fellow, Bioorganic Chemistry, Yale University, 2002-06
National Institute of Health Postdoctoral Fellow, Bioorganic Chemistry, Yale University, 2002-06
Professional Involvement and Accomplishments
Ruth L. Kirschstein National Research Service Award, Individual Postdoctoral Fellowship, sponsored by the National Institute of Health/National Institute of General Medical Sciences, 2004-06
Expertise
Mechanistic Physical Organic Chemistry
RNA Chemical Biology
Solid Phase Organic Synthesis
Synthetic Organic Chemistry
Special Interests and Activities
Project SEED program titled "Role of Organic Synthesis in Drug Discovery," sponsored by The American Chemical Society (ACS) and Azusa Pacific University
Note: This information is current for the 2007-08 academic year. For additional information, please contact the appropriate office.
